Polyoxovanadate-IodoBodipy Supramolecular Assemblies: New Agents for High Efficiency Cancer Photochemotherapy
2020
Two novel polyoxovanadate-iodoBodipy supramolecular assemblies, named as (2I-BDP-C6)2V6 and (2I-BDP-C6)3V10, were first synthesized by self-assembly of anionic hexavanadate and decavanadate with cationic iodoBodipy for photochemotherapy, respectively. The mechanisms for synergistic photochemotherapy of anion-cation pairs were forced on. In particular, (2I-BDP-C6)3V10 is the first example of polyoxovanadates used for photochemotherapy which can effectively kill lung cancer cells (HepG2) by synergetic chemotherapy as well as photodynamic therapy.
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