A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs

David L. Mellman,Michael L. Gonzales,Chunhua Song,Christy A. Barlow,Ping Wang,Christina Kendziorski,Richard A. Anderson

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs

2008

David L. Mellman
Michael L. Gonzales
Chunhua Song
Christy A. Barlow
Ping Wang
Christina Kendziorski
Richard A. Anderson

A new polyadenylation polymerase, called Star-PAP, is identified, the activity of which is regulated by nuclear phosphoinositides generated by the kinase PIPKIα.

Keywords:

Enzyme
Gene expression
Polynucleotide adenylyltransferase
Polymerase
Polyadenylation
Kinase
Nucleotidyltransferase
Messenger RNA
Biochemistry
Biology
Cytosol
Gene
Effector

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