A model explaining synchronization of neuron bioelectric frequency under weak alternating low frequency magnetic field

Abstract A biomagnetic-electrical model is presented that explains rather well the experimentally observed synchronization of the bioelectric potential firing rate (“frequency”), f , of single unit neurons of Helix aspersa mollusc under the application of extremely low frequency (ELF) weak alternating (AC) magnetic fields (MF). The proposed model incorporates to our widely experimentally tested model of superdiamagnetism (SD) and Ca 2+ Coulomb explosion (CE) from lipid (LP) bilayer membrane (SD–CE model), the electrical quadrupolar long range interaction between the bilayer LP membranes of synchronized neuron pairs, not considered before. The quadrupolar interaction is capable of explaining well the observed synchronization. Actual extension of our SD–CE-model shows that the neuron firing frequency field, B , dependence becomes not modified, but the bioelectric frequency is decreased and its spontaneous temperature, T , dependence is modified. A comparison of the model with synchronization experimental results of pair of neurons under weak ( B 0 ≅ 0.2–15 mT) AC-MF of frequency f M =50 Hz is reported. From the deduced size of synchronized LP clusters under B , is suggested the formation of small neuron networks via the membrane lipid correlation.