Comprehensive flow cytometric reference intervals of leukocyte subsets from six study centers across Europe

A group of European FOCIS Centers of Excellence adapted panels of the Human Immunophenotyping Consortium (HIPC) for whole blood analysis. Using 4 core panels (T/Treg/B/NK and myeloid cells) the main leukocyte populations were analyzed in a clinical-diagnostic setting in a harmonized way across different platforms. As a first step, the consortium presents here the absolute and relative frequencies of the leukocyte subpopulations in the peripheral blood of more than 300 healthy volunteers across 6 different European centers.