Amlodipine interfere in serum albumin binding of loasrtan and its active metabolite losartan carboxylic acid (EXP- 1734): Contra-contemporary in vitro approaches

The combination therapy of Losartan (LOS) and amlodipine (AMLO) has proven to be beneficial as compared to either individual drug monotherapy. Nonetheless, the mechanism of a beneficial effect is y...