Abstract 234: Nuclear Export of Telomeric Repeat Binding Factor 2 (terf2)-interacting Protein (terf2ip) Expression, One of the Sherterin Complex Molecule, is Crucial for Disturbed Flow-induced Endothelial Inflammation and Senescence via Upregulating Terf2ip S205 Phosphorylation

Hang T Vu,Nhat Tu Le,Kyung-Sun Heo,Yuka Fujii,Sivareddy Kolta,Kyung Ae Ko,Yin Wang,Tamlyn Thomas,Elena Fujiwara,Carolyn Giancursio,Keigi Fujiwara,Jun-ichi Abe

Abstract 234: Nuclear Export of Telomeric Repeat Binding Factor 2 (terf2)-interacting Protein (terf2ip) Expression, One of the Sherterin Complex Molecule, is Crucial for Disturbed Flow-induced Endothelial Inflammation and Senescence via Upregulating Terf2ip S205 Phosphorylation

2018

Hang T Vu
Nhat Tu Le
Kyung-Sun Heo
Yuka Fujii
Sivareddy Kolta
Kyung Ae Ko
Yin Wang
Tamlyn Thomas
Elena Fujiwara
Carolyn Giancursio
Keigi Fujiwara
Jun-ichi Abe

Atherosclerosis is a multifactorial disease mainly caused by endothelial cell (EC) dysfunction resulting from EC senescence. Both EC inflammation and senescence are increased by disturbed flow (d-f...

Keywords:

TERF2
Senescence
Cell biology
Phosphorylation
Inflammation
Molecule
Telomeric-Repeat Binding Factor
Biochemistry
Biology
Nuclear export signal
endothelial inflammation
disturbed flow

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