Conversion of aziridines to oxazolidines through geminal difunctionalization of vinyl arenes or by tandem ring-opening/closing reaction of aziridine itself
2016
Abstract One pot synthesis of 1,3-oxazolidines derivatives was developed by two different approaches. Aziridines were used in the first approach instead of amino alcohol. Whereas, in the second approach we have developed an unprecedented reaction where aziridine itself gave the desired product by the reaction with in situ generated ring opening product of the same aziridine. To the best of our knowledge there is no such report in the literature for this type of cyclization.
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