Anti-inflammatory effect of methanolic extract leaves ofAnogeissus accuminata

The aim of this study is to establish the anti-inflammatory activity of the Methanolic extract of Anogeissus accuminata leaves with its fractions and to delineate the possible mechanism of action of methanolic extract of Anogeissus accuminata. The anti-inflammatory activities of methanolic extract of Anogeissus accuminata was evaluated in a Dextran induced model of acute inflammation and the paw edema volume was measured. Methanolic extract of Anogeissus accuminata (300mg/kg, body wt, p.o) significantly reduced Dextran induced paw edema in rats. Methanolic extract of Anogeissus accuminata possesses significant anti-inflammatory activity.