Changes of Inbreeding Coefficient and Genic Heterozygosity in Closed Population under Random Selection

Monte Carlo computer simulation was used to determine the changes of inbreeding coefficients and genic heterozygosities in closed populations under different population sizes,male-female ratios and initial gene frequencies,which assumed that there was no gene mutation and individual immigration between populations. 10 bi-allelic gene loci were assumed on 10 different autosomes. Random selection and mating was implemented in all generations,the generation was non-overlapping and the numbers of breeding animals were kept equal in each generation. The simulation experiment had been carried out for 50 generations and 100 replications. The results showed that the smaller inbreeding increments and higher genic heterozygosity were gained for larger size population and more males; and the higher heterozygosity had been kept under medium level initial gene frequency. It was harmful for the maintaining of the within-population genetic diversity for smaller population,fewer males and lower or higher initial gene frequency.