Haplotype of platelet receptor P2RY12 gene is associated with residual clopidogrel on-treatment platelet reactivity

Xiao-yan Nie,Li Jf,Yong Zhang,Yang Xu,Xue-Li Yang,Yu Fu,Guang-kai Liang,Yun Lu,Jian Liu,Lu-wen Shi

Haplotype of platelet receptor P2RY12 gene is associated with residual clopidogrel on-treatment platelet reactivity

2017

Xiao-yan Nie
Li Jf
Yong Zhang
Yang Xu
Xue-Li Yang
Yu Fu
Guang-kai Liang
Yun Lu
Jian Liu
Lu-wen Shi

Objective To investigate a possible association between common variations of the P2RY12 and the residual clopidogrel on-treatment platelet reactivity after adjusting for the influence of CYP2C19 tested by thromboelastography (TEG).

Keywords:

Clopidogrel
Biochemistry
Thromboelastography
Haplotype
Gene
Platelet
Anesthesia
Biology
CYP2C19
Receptor
Pharmacology
Ticlopidine
Aspirin
Acute coronary syndrome

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