Antidiarrhetic loperamide hydrochloride.

Single crystals of the anhydrous form of the title compound {systematic name: 1-[3-(dimethyl­carbamo­yl)-3,3-diphenyl­prop­yl]-4-hy­droxy-4-(4-chloro­phen­yl)piperidin-1-ium chlor­ide}, C29H34ClN2O2+·Cl−, were obtained by diffusion of acetone into a solution in 2-propanol. In the structure, N—H⋯Cl− and O—H⋯Cl− hydrogen bonds connect neighbouring mol­ecules and chloride anions to form chains along the c-axis direction. Neighbouring chains along the b-axis direction are connected by inter­molecular C—H⋯Cl− con­tacts, defining layers parallel to the (100) planes. The layers are connected by weak inter­molecular C—H⋯Cl inter­actions only, which may account for the plate-like shape of the crystals.