Regulation of Hematopoiesis in Cancer Patients: Placebo-Driven, Double-Blind Clinical Trials of β-Glucan

AIM: The role of glucan in the stimulation of immunity is well established, including oncological models. In this report, we focused on effects of glucan supplementation of cancer patients in post-treatment periods. MATERIALS AND METHODS: We measured the levels of C-reactive protein, ferritin, transferrin, soluble transferrin receptors, hemoglobin, total number of erythrocytes and index of sTfR/log ferritin. RESULTS: We found significant improvements in the levels of hemoglobin, total number of erythrocytes and index of sTfR/log ferritin. CONCLUSIONS: We concluded that the short 60 day supplementation with orally-administered glucan significantly improved some parameters of hematopoiesis.