Immunoaffinity LC-MS/MS is more suitable than ELISA to quantify a PEGylated molecule in cynomolgus monkey serum.

Yanqiu Liu,Luna Liu,Nancy Yu,Lu Dai,Cinzia Stella,Vincent Chang,Surinder Kaur,Keyang Xu,Eric Wakshull

Immunoaffinity LC-MS/MS is more suitable than ELISA to quantify a PEGylated molecule in cynomolgus monkey serum.

2020

Yanqiu Liu
Luna Liu
Nancy Yu
Lu Dai
Cinzia Stella
Vincent Chang
Surinder Kaur
Keyang Xu
Eric Wakshull

Background: Polyethylene glycolylation (PEGylation) technology is a long-acting delivery platform used to increase the half-life of protein therapeutics. Quantitation of PEGylated anti-Factor D Fab...

Keywords:

Chemistry
Protein therapeutics
lc ms ms
Chromatography
Molecule
PEGylation

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