AB179. CMTM3 is reduced in prostate cancer and inhibits migration, invasion and growth of LNCaP cells

Objective A novel tumor suppressor gene (TSG) CKLF-like MARVEL transmembrane domain-containing member 3 (CMTM3) is reduced or undetectable in many kinds of cancers and relates tumor malignant features. We detected its role in prostate cancer for possibility of target therapy as accumulating evidence has shown that CMTM3 is a promising TSG for gene therapy.