Functional Neuropharmacology of Compounds Acting at 5-HT1B/D Receptors

The neuropharmacology of serotonin (5-HT) has been fundamentally revised in recent years with the discovery of multiple serotonin receptor subtypes. Detailed descriptions of the pharmacology of the various receptor subtypes are to be found elsewhere in this book. We review here the available data on the in vitro and in vivo neuropharmacology of the 5-HT1B/D group of receptor subtypes and attempt to identify their possible functions and potential implications in psychiatric disorders.