R (+) - lipoic acid -l- preparation of new crystalline form and lysine salt
2015
The present invention relates to the field of pharmaceutical chemistry, in particular to a R (+) - lipoic acid -L- lysine salt novel crystalline form, i.e., the crystal form Ⅰ their preparation. The present invention further relates to a new crystalline form of the pharmaceutical composition, its application in paresthesia medicament for the treatment of diabetic peripheral neuropathy is caused. The R (+) - lipoic acid -L- lysine salt Form Ⅰ, using Cu-Kα radiation, X- ray powder diffraction at 2θ angles shown in the 5.102,7.589,10.072,12.549,15.036,16.688, 18.627,19.356,25.064,27.611 diffraction peak at which the 2θ value of the error range is ± 0.2.
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