Nanobarcodes™ Identification Tags in Proteomics and Small Molecule Profiling

We describe novel applications of Nanobarcodes™ Identification Tags (NBCs), nanometer-scale metallic bar codes in proteomics and small molecule profiling. Synthesis, detection and surface derivatization of these nanoparticles are presented. Solid-phase nanoextraction (SPNE) of analytes from biological samples and its unique application in MALDI-TOF mass spectrometry are detailed.