Exome sequence genotype imputation in globally diverse hexaploid wheat accessions

Fan Shi,Josquin Tibbits,Raj K. Pasam,Pippa Kay,Debbie Wong,Joanna Petkowski,Kerrie L. Forrest,Ben J. Hayes,Alina Akhunova,John P. Davies,Steven R. Webb,German Spangenberg,Eduard Akhunov,Matthew J. Hayden,Hans D. Daetwyler

Exome sequence genotype imputation in globally diverse hexaploid wheat accessions

2017

Fan Shi
Josquin Tibbits
Raj K. Pasam
Pippa Kay
Debbie Wong
Joanna Petkowski
Kerrie L. Forrest
Ben J. Hayes
Alina Akhunova
John P. Davies
Steven R. Webb
German Spangenberg
Eduard Akhunov
Matthew J. Hayden
Hans D. Daetwyler

Key message Imputing genotypes from the 90K SNP chip to exome sequence in wheat was moderately accurate. We investigated the factors that affect imputation and propose several strategies to improve accuracy.

Keywords:

Genetics
Exome
SNP genotyping
Biology
Imputation (statistics)
Genotype
Bioinformatics
SNP
Single-nucleotide polymorphism
exome capture
Genetic marker
Genetic association

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations