Preparation method of 3-methyl-2-ethanol based quinoxaline

The invention discloses a preparation method of 3-methyl-2-ethanol based quinoxaline, comprising the following steps of: (1) in a solvent, carrying out reduction reaction on maquindox in the presence of a reducing agent to obtain 3-methyl-2-acetylquinoline; and (2) in the solvent, carrying out the reduction reaction on the 3-methyl-2-acetylquinoline in the presence of the reducing agent to obtain the 3-methyl-2-ethanol based quinoxaline. The 3-methyl-2-ethanol based quinoxaline of the invention is quinoxaline drug metabolites and can be used as a standard product for the residual and metabolism researches on quinoxaline drugs.