The interleukin-2 receptor: a target for immunotherapy.

Immune intervention began almost two centuries ago when Jenner introduced vaccination with cowpox as a means of protecting against smallpox. This form of immune intervention plays a dominant role in the prevention of human disease. Furthermore, immunological approaches including radioimmunoassays, enzyme-linked immunoassays, microfluorometry, and modern molecular immunogenetics are critical in clinical diagnosis.