High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.

De Xie,Hairong Zhao,Jiaming Lu,Furong He,Weidong Liu,Wei Yu,Qiang Wang,Ichiro Hisatome,Tetsuya Yamamoto,Hidenori Koyama,Jidong Cheng

High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.

2021

De Xie
Hairong Zhao
Jiaming Lu
Furong He
Weidong Liu
Wei Yu
Qiang Wang
Ichiro Hisatome
Tetsuya Yamamoto
Hidenori Koyama
Jidong Cheng

Uric acid is the end metabolite derived from the oxidation of purine compounds. Overwhelming evidence shows the vital interrelation between hyperuricemia (HUA) and non-alcoholic fatty liver disease...

Keywords:

Internal medicine
Purine
liver fat
Chemistry
Endocrinology
Uric acid
Oxidative stress
Fatty liver
Hyperuricemia
Metabolite

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