Assessment of human exposure to environmental sources of lead arising from the lead battery manufacturing and recycling sector in Europe: demonstration of a tiered approach in a case study.

BACKGROUND Standard approaches for the assessment of Man via the Environment exposure are designed to be conservative. However, propagating these exposures into health impact assessment might lead to questionable socio-economic costs. OBJECTIVE The objective of this study was to develop a novel tiered modelling approach to assess human exposure to lead (Pb) via the environment. METHOD The approach starts in Tier 1 from EUSES modelling approach, modified with metal specific transfer factors. The generic Tier 2 approach uses the higher tier model GPM for air quality, and dietary exposure modelling based on EFSA's Comprehensive Food Database, in combination with crop specific transfer factors. Tier 3 considers additional site-specific information such as proximity of inhabitants and agricultural activities in relation to industrial sites. RESULTS This tiered modelling approach was applied to a case study of 50 lead battery manufacturing and recycling sites across Europe. Data sets from general population human biomonitoring studies were used to compare the predicted additional bioburden of Pb resulting from lead battery manufacturing and recycling. The higher tier assessments were able to demonstrate a >20-fold reduction in modelled Pb exposure compared to default assumptions made in Tier 1. SIGNIFICANCE Leading to better estimates for socio-economic costs in health impact assessment.