Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice
2016
Rationale
Although leptin receptors are found in hypothalamic nuclei classically associated with homeostatic feeding mechanisms, they are also present in brain regions known to regulate hedonic-based feeding, natural reward processing, and responses to drugs of abuse. The ob/ob mouse is deficient in leptin signaling, and previous work has found altered mesolimbic dopamine signaling and sensitivity to the locomotor activating effects of amphetamine in these mice.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
68
References
16
Citations
NaN
KQI