Extraction technology of serotonin derivatives from seed meal of Hehuang Carthamus tinctorius L. by water reflux method.

[Objective] To optimize the extraction technology of serotonin derivatives from seed meal of Hehuang Carthamus tinctorius L.by water reflux method.[Method] Taking the content of serotonin derivatives as index,the extraction technology of serotonin derivatives was optimized by means of orthogonal test with extraction temperature,extraction time,extraction times and solid-liquid ratio as experimental factors.[Result] The extraction of serotonin derivatives from seed meal of Hehuang C.tinctorius was impacted mostly by extraction temperature,followed by extraction time,extraction times and solid-liquid ratio.The optimal technology was extraction temperature of 80 ℃,extraction time of 1.5 h,extraction times of 3 and solid-liquid ratio of 1∶ 20 g/ml,with which the content of f serotonin derivatives was 0.70%.[Conclusion] This optimal extraction technology could provide basis for the development and production of Hehuang C.tinctorius seed meal.