A G-quadruplex aptamer inhibits the phosphatase activity of oncogenic protein Shp2 in vitro.

Jia Hu,Jie Wu,Cong Li,Ling Zhu,Wei Yun Zhang,Guiping Kong,Zhongxian Lu,Chaoyong James Yang

A G-quadruplex aptamer inhibits the phosphatase activity of oncogenic protein Shp2 in vitro.

2011

Jia Hu
Jie Wu
Cong Li
Ling Zhu
Wei Yun Zhang
Guiping Kong
Zhongxian Lu
Chaoyong James Yang

Natural Science Foundation of Fujian Province, China[2008J0107, 2010J06004]; National Scientific Foundation of China[20805038, 21075104, 30772546]; National Basic Research Program of China[2007CB935603, 2010CB732402, 2010CB945004]

Keywords:

Systematic evolution of ligands by exponential enrichment
G Quadruplexes
Molecular biology
G-quadruplex
Aptamer
Phosphatase
In vitro
Biochemistry
Chemistry
basic research

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