A Cycloaddition—Cyclization Combined Approach to Enantiopure 3‐Glycinyl‐4‐hydroxypyrrolidines and 3‐Substituted 4‐Hydroxyprolines.

1,3-Dipolar cycloaddition of a (-)-menthone derived nitrone as glycine equivalent with (E)- or (Z)-1,4-dichloro-2-butene affords bis(chloromethyl) substituted isoxazolidine cycloadducts.