Lissencephaly with agenesis of corpus callosum: A rare anomaly

Lissencephaly means smooth cerebrum with lack of normal convolutions of brain. It is a rare disorder caused by defect in migration of neurons, which occurs between 12 and 24 weeks of gestation period. The prevalence of type I lissencephaly in Netherlands was found to be 11.7 per million births. It may be associated with other developmental anomalies in brain, such as cerebellar hypoplasia and pachygyria, but its association with agenesis of corpus callosum is very rare. We present a case of lissencephaly with corpus callosal agenesis.