Anti-inflammatory Potential of Flavonoids from the Aerial Parts of Corispermum marschallii

The isolation of phenolics from aerial parts of Corispermum marschallii yielded a total of 13 compounds including nine previously undescribed patuletin and spinacetin glycosides. These were identified as patuletin 3-O-β-d-galactopyranosyl-7-O-β-d-glucopyranoside (1), spinacetin 3-O-β-d-galactopyranosyl-7-O-β-d-glucopyranoside (2), patuletin 3-O-(6″-O-β-d-glucopyranosyl)-β-d-galactopyranoside (3), patuletin 3-O-(6″-O-α-l-arabinopyranosyl)-β-d-galactopyranoside (4), patuletin 3-O-(2″-O-(5‴-O-α-l-arabinopyranosyl)-β-d-apiofuranosyl)-β-d-galactopyranoside (5), patuletin 3-O-(2″-O-β-d-apiofuranosyl)-β-d-galactopyranoside (6), spinacetin 3-O-β-d-galactopyranoside (7), patuletin 3-O-β-d-galactopyranosyl-7-O-(6‴-O-feruloyl)-β-d-glucopyranoside (8), and spinacetin 3-O-β-d-galactopyranosyl-7-O-(6‴-O-feruloyl)-β-d-glucopyranoside (9). Structure elucidation was based on UV–visible, multistage MS, and 1D and 2D NMR spectroscopy and chemical derivatization, which allowed the identification on the glycosides with two di...