The Cyclone 30XP multiparticles cyclotron and At-211, Cu-67 production

2011 
1514 Objectives To reply to the strong demand of researchers and the need of specific radio nuclides for nuclear medicine in the field of therapy, especially 211At and 67Cu for radio immunotherapy, IBA propose a Cyclone® 30-XP multiparticule cyclotron. 211At is uniquely produced by alpha beam of 29MeV onto natural Bismuth target. 67Cu production route with alpha beam can be explored as well. Availability of deuteron beam of higher energy will allow testing of (d,xn) nuclear reaction for new radioisotope production (ex. 64Cu). Methods While proton (15-30 MeV) and deuteron (8-15 MeV) are produced and extracted in the well-known negative ion mode with stripping extraction in the Cyclone® 30, the positive alpha beam (nucleus of helium atom He+) is accelerated and extracted in positive ion mode using an electrostatic deflector. The He2+ acceleration needs specific external source and adjustments to the cyclotron magnetic field and acceleration frequency (RF). The energy of the alpha beam will be fixed in the 29-30 MeV range. Redesign of the magnet system was needed to leave free space for the alpha deflector and to reuse magnetic ‘flaps’ for field correction as it is done on the IBA-Cyclone® 18/9. Pole extensions gradient correctors were reused from the Cyclone®70 to ease alpha beam extraction. Results Some technical challenges were solved to fit the two RF acceleration modes in the same machine with external ion sources platform for the different ions species. Another challenge was solved by using the magnetic deep-valley concept which allows housing the alpha deflector to a common exit used for both modes. This allows the use of one common beam line and solid target system for both proton and alpha beams. Conclusions The design is completed, the machining and magnetic mapping is done (march 2010) and the first Cyclone®30 -XP is foreseen for installation at Forschungszentrum Julich, Germany in the beginning of 2011. The production of both At-211 and Cu-67 could benefit from this new machine design
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