Transition-Metal and Solvent-Free Oxidative C–HFluoroalkoxylation of Quinoxalinones with Fluoroalkyl Alcohols
2019
The first example of oxidative C–H fluoroalkoxylation of quinoxalinones with fluoroalkyl alcohols under transition-metal and solvent-free conditions is described. This approach provides the synthesis of fluoroalkoxylated quinoxaline derivatives with good to excellent yields under mild reactions conditions. This method can also be extended to the facile and efficient synthesis of histamine-4 receptor.
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