6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A 2 α Activity.

Purnima Singh,Chi Young Song,Shubha Ranjan Dutta,Ajeeth K. Pingili,Ji Soo Shin,Frank J. Gonzalez,Joseph V. Bonventre,Kafait U. Malik

6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A 2 α Activity.

2021

Purnima Singh
Chi Young Song
Shubha Ranjan Dutta
Ajeeth K. Pingili
Ji Soo Shin
Frank J. Gonzalez
Joseph V. Bonventre
Kafait U. Malik

This study was conducted to test the hypothesis that the CYP1B1 (cytochrome P450 1B1)-testosterone metabolite 6β-hydroxytestosterone contributes to angiotensin II-induced hypertension by promoting ...

Keywords:

Internal medicine
Metabolite
Angiotensin II
Testosterone
Blood pressure
CYP1B1
Endocrinology
Renin–angiotensin system
Phospholipase A
Cytosol
Chemistry

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