Mosaic 46,XY/92,XXYY,de1(5)(q13 q34) in an adult lymphoblastic leukemia
1991
Abstract Usually the chromosome anomalies encountered in ALL are modal number abnormalities (hyperdiploidy or hypodiploidy) and structural anomalies such as t(8;14), t(11;14), t(9;22), t(1;19) and del(6p). The 5q- syndrome is mainly associated with myelodysplastic syndromes and with ANLL (M1, M2, M3). We report the case of a patient presenting with a mosaic karyotype 46,XY/ 92,XXYY,del(5)(q13 q34) in the following proportion 1 3 normal mitoses and 2 3 tetraploid mitoses.
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