Synthesis and Activity of Phenyl Derivatives Containing 5,6-Dimethylthieno[2,3-d]pyrimidin-4(1H)-one or 4H-Pyrimido [5,4-b] indol-4-one Heterocyclic System as Potential Non-steroidal Anti-inflammatory Drugs
2011
The synthesis, the analgesic and anti-inflammatory activities of two series of phenyl derivatives containing 5,6-dimethylthieno[2,3-d]pyrimidin-4(1H)-one and 4H-pyrimido[5,4-b]indol-4-one system, respectively, are reported. Two of these derivatives, 6A and 9B, showed interesting activities. The results of the pharmacological assays are discussed.
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