Stereoselective Synthesis of 2′-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential anti-HCV Agents.

Stereoselective synthesis of 2‘-C-methyl-cyclopropyl-fused carbanucleosides was accomplished via stereoselective cyclopropanation, regioselective cleavage of the isopropylidene group, stereoselective Grignard reaction, and cyclic sulfate chemistry.