N-Acylsuccinimides: Efficient acylative coupling reagents in palladium-catalyzed Suzuki coupling via CN cleavage

Abstract An acylative Suzuki coupling of activated amides with aryl boronic acids has been reported via palladium-catalyzed C N bond cleavage. This protocol demonstrate amides can be activated by an atom-economic and cheap succinimide, which can be efficiently utilized to synthesize broad array of diaryl ketones in moderate to good yields.