Impact of the Charge Ratio on the In Vivo Immunogenicity of Lipoplexes

Zahra Heidari,Jaspreet Arora,Dibyadyuti Datta,Vijay T. John,Nirbhay Kumar,Geetha P. Bansal

Impact of the Charge Ratio on the In Vivo Immunogenicity of Lipoplexes

2017

Zahra Heidari
Jaspreet Arora
Dibyadyuti Datta
Vijay T. John
Nirbhay Kumar
Geetha P. Bansal

Purpose The present study investigated the immunogenic potential of different cationic liposome formulations with a DNA plasmid encoding Pfs25, a malaria transmission-blocking vaccine candidate.

Keywords:

Plasmid
Immunogenicity
Lipoplex
In vivo
Cationic liposome
Chemistry
Virology
Molecular biology
Biochemistry
Adjuvant
DNA vaccination
Electroporation
Flow cytometry

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