Benzimidazole CB2 agonists: design, synthesis and SAR.

Kausik K. Nanda,Darrell A. Henze,Kimberly Della Penna,Reshma Desai,Michael D. Leitl,Wei Lemaire,Rebecca B. White,Suzie Yeh,Janine N. Brouillette,George D. Hartman,Mark T. Bilodeau,B. Wesley Trotter

Benzimidazole CB2 agonists: design, synthesis and SAR.

2014

Kausik K. Nanda
Darrell A. Henze
Kimberly Della Penna
Reshma Desai
Michael D. Leitl
Wei Lemaire
Rebecca B. White
Suzie Yeh
Janine N. Brouillette
George D. Hartman
Mark T. Bilodeau
B. Wesley Trotter

Abstract A new series of CB2-selective agonists containing a benzimidazole core is reported. Design, synthesis, SAR and pharmacokinetic data for selected compounds are described.

Keywords:

Medicinal chemistry
Organic chemistry
Benzimidazole
Pharmacokinetics
Chemistry
cb2 agonist
design synthesis

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