Central, but not peripheral administration of opioids is beneficial in experimental acute pancreatitis

Janneke van Grinsven , Sandra van Brunschot , Olaf Bakker , Thomas Bollen , Marja Boermeester , Marco Bruno , Kees Dejong , Marcel Dijkgraaf , Casper van Eijck , Paul Fockens , Harry van Goor , Hein Gooszen , Karen Horvath , Krijn van Lienden, Hjalmar van Santvoort , Marc Besselink d a Academic Medical Center Amsterdam, Dept. of Gastroenterology/ Surgery, Netherlands University Medical Center Utrecht, Dept. of Surgery, Netherlands c St. Antonius Hospital Nieuwegein, Dept. of Radiology, Netherlands Academic Medical Center Amsterdam, Dept. of Surgery, Netherlands e Erasmus Medical Center Rotterdam, Dep. of Gastroenterology, Netherlands Maastricht University Medical Center, Dept. of Surgery, Netherlands Academic Medical Center Amsterdam, Clinical Research Unit, Netherlands h Erasmus Medical Center Rotterdam, Dept. of Surgery, Netherlands i Academic Medical Center Amsterdam, Dept. of Gastroenterology, Netherlands j Radboud University Medical Center, Dept. of Surgery, Netherlands k Radboud University Medical Center, Dept. of OR/Evidence Based Surgery, Netherlands l University of Washington, Dept. of Surgery, United States Academic Medical Center Amsterdam, Dept. of Radiology, Netherlands