REALIZATION OF HIGH REGIOSELECTIVITY IN THE COUPLING REACTION OF A CYCLOPENTADIENE MONOEPOXIDE EQUIVALENT AND ARYL NUCLEOPHILES

Abstract Coupling reaction of monoacetate 2 and aryl hard nucleophiles is realized for the first time, which consists of the lithium arylborates as hard nucleophiles and NiCl 2 (PPh 3 ) 2 as a catalyst. More importantly, the independent effects of t -BuCN and NaI and their synergistic function are discovered to increase regioselectivity furnishing trans 1,3-isomers 6 as the major products.