Synthesis of 2-(4-chlorophenyl)-6-methyl- 3-[1-aryl-2-prop-en-1-ones-3-yl] / (3 aryl - 4,5-dihydro-1-H-pyrazol-5-yl)/(3-arylisoxazole-5-yl) - imidazo[1,2-a]pyridine
2009
2-(4i¢-chlorophenyl)-6-methyl-3-[1i¢i¢-aryl- 2i¢i¢-prop-en-1i¢i¢-ones-3-yl)-imidazol [1,2,-a]pyridines. (3a-31) ;2-(4'-chlorophenyl)-6-methyl-(3i¢i¢-aryl-4i¢i¢,5i¢i¢- dihydro-1i¢i¢-Hpyrazol-5i¢i¢-yl)imidazo[1,2a]pyridine(4a-41);2-(4'-chlorophenyl) -6-methyl-3-(3i¢i¢-arylisoxazole-5i¢i¢-yl)-imidazo [1,2-a]pyridine(5a-5l) have been synthesized. The products have been assayed for their biological activity againstGram+ve,GramÂve bacteria and fungi. Some of the products showed moderate activity in concentration 50ig. The structures of the products have been elucidated by IR, 1H NMR,Mass spectral data, elemental analysis and thin layer chromatography.
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