Measurement of hepatic blood flow by clearance methods

The estimation of hepatic and splanchnic blood flow in humans by clearance methods has been reviewed (Part I). Methods based on the Fick principle and hepatic vein catheterization employ BSP, Rose Bengal, urea, or galactose as the test substance. Methods based on the disappearance of particulate material after injection use P32-labeled colloidal chromic phosphate, Au198-labeled colloidal gold, or I131-labeled denatured human serum albumin as the test substance.