Synthesis, crystal structure, thermal studies and antimicrobial activity of a mononuclear Cu(II)-cinnamate complex with N,N,N′,N′-tetramethylethylenediamine as co-ligand

Abstract The reaction of copper(II) chloride dihydrate, cinnamic acid and N,N,N′,N′-tetramethylethylenediamine afforded a monomeric complex [Cu(tmeda)(cinnamate)2]·0.7H2O (1) (Where tmeda = N,N,N′,N′-tetramethylethylenediamine). The synthesized complex 1 was characterized by means of elemental combustion analysis, thermogravimetric analysis, spectroscopic measurements (Uv-Visible, FTIR spectroscopy) and single crystal analysis. The coordination geometry of complex 1 is a distorted octahedron, having cinnamate1- ions coordinated to Cu2+ ion as asymmetric bidentate ligands while N,N,N′,N′-tetramethylethylenediamine is coordinated Cu2+ ion in a symmetric bidentate chelating mode, forming a five-membered chelate ring containing copper(II) ion. The crystal lattice in 1 is stabilized by intermolecular O–H⋯O hydrogen bonding interactions. The intermolecular O–H⋯O interactions between lattice H2O molecules and cinnamate groups propagate the monomeric units of complex 1 into 1D-chain motifs. Antimicrobial properties of the complex 1 were evaluated and the results showed that it exhibited remarkable activities against Bacillus spizizenii, and Staphylococcus aureus. A moderate activity against Enterobacter aerogenes, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa was observed. No activity was observed against Salmonella enterica, and the fungal strain Aspergillus niger.