Ubiquitin-Specific Peptidase USP22 Negatively Regulates the STAT Signaling Pathway by Deubiquitinating SIRT1

Ning Ao,Yanyan Liu,Hailiang Feng,Xiaocui Bian,Zhanwen Li,Bei Gu,Xiaomei Zhao,Yuqin Liu

Ubiquitin-Specific Peptidase USP22 Negatively Regulates the STAT Signaling Pathway by Deubiquitinating SIRT1

2014

Ning Ao
Yanyan Liu
Hailiang Feng
Xiaocui Bian
Zhanwen Li
Bei Gu
Xiaomei Zhao
Yuqin Liu

Background/Aims: The ubiquitin-specific peptidase USP22 mediates various cellular and organismal processes, such as cell growth, apoptosis, and tumor malignancy.

Keywords:

Acetylation
STAT3
Ubiquitin
Cell growth
Apoptosis
Signal transduction
Cancer research
Malignancy
Biology
HEK 293 cells
Small interfering RNA
Regulator
Biochemistry

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