Line-field confocal optical coherence tomography operating simultaneously at 800 nm and 1300 nm center wavelengths

Line-field confocal optical coherence tomography (LC-OCT) is a new technology that combines the principles of time-domain OCT and reflectance confocal microscopy for cross-sectional imaging of biological samples in vivo at a cellular level in real-time. Dual-band LC-OCT is an extension of LC-OCT, operating simultaneously in two spectral bands. The short wavelengths yield ultrahigh-resolution images whereas the longer display extended penetration depth. Greyscale compounding has been implemented to yield a single greyscale image with both high resolution and extended depth penetration. Color fusion was done to emphasize differences of spectroscopic properties in the sample and to enhance the image contrast. The technology is applied in dermatology.