Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced kidney injury.

Catalina Sierra-Ramos,Silvia Velazquez-Garcia,Ayse Gokce Keskus,Arianna Vastola-Mascolo,Ana Elena Rodríguez-Rodríguez,Sergio Luis-Lima,Guadalberto Hernández,Juan F. Navarro-González,Esteban Porrini,Ozlen Konu,Diego Alvarez de la Rosa

Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced kidney injury.

2021

Catalina Sierra-Ramos
Silvia Velazquez-Garcia
Ayse Gokce Keskus
Arianna Vastola-Mascolo
Ana Elena Rodríguez-Rodríguez
Sergio Luis-Lima
Guadalberto Hernández
Juan F. Navarro-González
Esteban Porrini
Ozlen Konu
Diego Alvarez de la Rosa

The serum and glucocorticoid-induced kinase 1 (SGK1) stimulates aldosterone-dependent renal Na+ reabsorption and modulates blood pressure. In addition, genetic ablation or pharmacological inhibitio...

Keywords:

Aldosterone
Kinase
Mineralocorticoid
Mineralocorticoid receptor
Reabsorption
Blood pressure
Chemistry
SGK1
Fibrosis
Endocrinology
Internal medicine

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