Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea.

Five new monoterpene glycosides, rhodiolosides A—E (1—5), were isolated from the roots of Rhodiola rosea (Crassulaceae). Their structures were elucidated as (2E,6E,4R)-4,8-dihydroxy-3,7-dimethyl-2,6-octadienyl β-D-glucopyranoside (1), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl α-D-glucopyranosyl(1→6)-β-D-glucopyranoside (2), (2E,4R)-4-hydroxy-3,7-dimethyl-2,6-octadienyl β-D-glucopyranosyl(1→3)-β-D-glucopyranoside (3), (2E,4R)-4,7-dihydroxy-3,7-dimethyl-2-octenyl β-D-glucopyranoside (4), and (2E)-7-hydroxy-3,7-dimethyl-2-octenyl α-L-arabinopyranosyl(1→6)-β-D-glucopyranoside (5), on the basis of various spectroscopic analyses and chemical degradation.