Pyrimidines as inhibitors of kinases

A compound selected from the group comprising: 4-Benzyloxy-6- [5- (3-methoxy-phenyl) -pyridin-3-yl] -2-pyridin-2-yl-pyrimidine, (4-Isopropyl-piperazin-1 -yl) - {4- [5- (2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -phenyl} -methanone, 4- {5- [4- (4-Isopropyl piperazin-1-ylmethyl) -phenyl] -pyridin-3-yl} -2-pyridin-5-yl-pyrimidine 2, 3- [2- (6-pyridin-3-yl-2-pyridin-2-yl -pyrimidin-4-yloxy) -ethyl] -1H-indole, 3- {2- [2- (6-Methyl-pyridin-2-yl) -6-pyridin-3-yl-pyrimidin-4-yloxy] - ethyl} -1H-indol, (4- {5- [6-Chloro-2- (6-methyl-pyridin-2-yl) -pyrimidin-4-yl] -pyridin-3-yl} -phenyl) - ( 4-isopropyl-piperazin-1-yl) -methanone, (4- {5- [6-Benzyloxy-2- (6-methyl-pyridin-2-yl) -pyrimidin-4-yl] -pyridin-3-yl } -phenyl) - (4-isopropyl-piperazin-1-yl) -methanone, (4-isopropyl-piperazin-1-yl) - (4- {5- [6-methoxy-2- (6-methylpyridin -2-yl) -pyrimidin-4-yl] -pyridin-3-yl} -phenyl) -methanone, (4- {5- [6-Hydroxy-2- (6-methyl-pyridin-2-yl) - pyrimidin-4-yl] -pyridin-3-yl} -phenyl) - (4-isopropyl-piperazin-1-yl) -methanone, {4- [5- (6-Chloro-2-pyridin-2-yl- pyrimidin-4-yl) -pyridin-3-yl] -phenyl} - (4 -isopropyl-piperazin-1-yl) -methanone, {4- [5- (6-Benzyloxy-2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -phenyl} - (4 -isopropyl-piperazin-1-yl) -methanone, {4- [5- (6-isopropoxy-2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -phenyl} - (4 -isopropyl-piperazin-1-yl) -methanone, 4-tert-Butyl-6- {5- [4- (4-methyl-piperazin-1-ylmethyl) -phenyl] -pyridin-3-yl} -2- pyridin-2-yl-pyrimidine, Dimethyl - ((R) -1- {4- [5- (2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -benzyl} -pyrrolidin -3-yl) -amine, Dimethyl - ((R) -1- {3- [5- (2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -benzyl} -pyrrolidin -3-yl) -amine, (4- {5- [6-Chloro-2- (6-methyl-pyridin-2-yl) -pyrimidin-4-yl] -pyridin-3-yl} -phenyl) - (3-dimethylaminopyrrolidin-1-yl) -methanone, (1- {4- [5- (6-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl) -pyridin-3-yl] -benzyl} -pyrrolidin-3-yl) -dimethyl-amine, (4- {5- [6-Benzyloxy-2- (6-methyl-pyridin-2-yl) -pyrimidin-4-yl] -pyridin-3-yl} -phenyl) - (3-dimethylaminopyrrolidin-1-yl) -methanone, 4-tert-Butyl-6- {5- [4- (4-methyl-piperazin-1-ylmethyl) -phenyl] -pyridin-3-yl } -2- (6-methyl-pyridin-2-yl) -pirimi dyne, and free or salt or solvate forms thereof.