An Eco-Friendly Paradigm for the Production of Potentially Anti-Parasitic Drugs

A cleaner production of various potentially anti-parasitic drugs based bis-(arylmethylidene)cycloalkanones have been developed using a heterogeneous catalysis technology in aqueous media without organic solvent. The higher activity and selectivity of our solid-state synthetic phosphate catalyst coupled with their ease of use and reduced environmental problems makes them attractive alternatives to homogeneous basic reagents.