Synthesis of amino alcohols from eugenol and their insecticidal activity against Sf 9 cell line

Eugenol is a major constituent of clove essential oil with interesting biological activity, namely antimicrobial and antioxidant. Structural changes of eugenol are a useful strategy in order to improve biological activity and at the same time obtain new analogues with reduced side effects. In this work, a series of amine nucleophiles were reacted with eugenol epoxide so as to obtain the corresponding amino alcohols, considering their potential as biopesticides. These eugenol amino alcohols were evaluated against insect cells, specifically the Sf9 cell line.