Design and Synthesis of Biotinylated DHMEQ for Direct Identification of Its Target NF-ϰB Components.

Tsuyoshi Saitoh,Masatoshi Takeiri,Yuko Gotoh,Yuichi Ishikawa,Kazuo Umezawa,Shigeru Nishiyama

Design and Synthesis of Biotinylated DHMEQ for Direct Identification of Its Target NF-ϰB Components.

2012

Tsuyoshi Saitoh
Masatoshi Takeiri
Yuko Gotoh
Yuichi Ishikawa
Kazuo Umezawa
Shigeru Nishiyama

The biotinylated dehydroxymethylepoxyquinomicin derivative (I) (one of two diastereomers shown) shows membrane permeability and combined selectivity with the target protein p65.

Keywords:

Diastereomer
Permeability (electromagnetism)
Biotinylation
Membrane
Selectivity
Target protein
Organic chemistry
Chemistry
membrane permeability

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